Unique Qualities of the Placenta
In Europe, the health improving and restoring benefits of human Placental Stem Cell Therapy have been well documented for more than 25 years. The incomparable contents of the placenta include very unique rejuvenating stem cells and powerful immune system substances including multiple hormones and growth factors including HGH, IGF-1 and multiple anti-inflammatory properties, to list a few. Nature’s placenta development powerhouse would be impossible to replicate which provides the explanation for the remarkable results achieved with this therapy.
The list below identifies the variety of substances found in full-term human placental tissue including the associated function. The presence of these substances and their function are well documented by multiple scientific publications including the Placenta International Journal offering validity to this unique therapy.
Substance |
Function |
| Human Growth Hormone (HGH) Insulin -like Growth Factor (IGF-1) |
Growth Factors |
| Corticotropin releasing Hormone (CRH) Adrenocorticotropic Hormone (ACTH) |
Anti-inflammatory effect |
| Gonadotropin Releasing Hormone (GnRH) | Releases Sexual Hormones |
| Interleukin - 6 (IL-6) | 1.B cell differentiation factor
(Hirano et al 1986). 2.Citotoxic T cell differentiation factor (Takai et al) 3.Hepatocyte Stimulating Factor (Gauldie et al) 4.Nerve differentiation Factor (Satoh et al 1988). 5.Promoter and mediator of Natural Immunity. |
| Interleukin- 10 (IL-10) | Down regulates cellular activation. Inhibits production of pro-inflammatory cytokines by monocytes and macrophages |
| Interferon-Alfa Interferon- Beta Interferon- Gamma |
Antiviral and anti-tumor activities, Activates macrophages. Enhances citotoxic lymphocyte and Natural Killer cell activity. |
| Tumor Necrosis Factor | Anti-tumor activity |
| Dynorphin | Endogenous Opiate |
| Vascular Endothelial Growth Factor | Angiogenesis |
| Inhibin, Activin and Follistatin | Regulatory proteins; Growth Factors; Immune Factors |
| Hepatocyte Growth Factor | Mesenchyme-ephithelial interactions |
| Carboxylesterases | Detoxification and metabolic activation of various drugs, environmental toxicants and carcinogens |
In addition to the substances listed above, the placenta has numerous Neuropeptides including Vasoactive Intestinal Polypeptide (VIP), Calcitonin Gene-related Peptide (CGRP), Somatostatin, Mmet-enkephaline, Helodermin and Substance P-like, Endothelin-1, Eritrophyotin (for bone marrow stimulation) all vitally important to optimum health. HGH (Human Growth Hormone) has been prescribed by physicians for anti-aging benefits and longevity purposes and recently Tumor Necrosis Factor was synthesized to treat ceratin cancers. Vascular Endothelial Growth Factor has also been reported for use in the therapy of Angina Pectoris. Interferon has been used to treat patients with Hepatitis C.
